25 Du Y* (* co-first author), Duc NM*, Kubiak X*, Kim HR, Manglik A, Kruse AC, Wegrecki M, Jeong KM, Lee J, Kobilka BK, Rasmussen SGF and Chung KY. Assembly of a GPCR-G protein complex. Nature, under revision

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24 Komolov KE*, Du Y* (* co-first author), Duc NM, Betz R, Rodrigues J, Leib RD, Patra D, Skiniotis G, Adams CM, Dror R, Chung KY, Kobilka BK, Benovic JL. Structural and functional analysis of a β2-Adrenergic Receptor Complex with GRK5. Cell (2017) 169: 407-421 –Selected as the Featured Article of the Issue

Recommended by F1000Prime: f1000.com/prime/727537208

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23 Das M*, Du Y* (* co-first author), Ribeiro O, Hariharan P, Mortensen JS, Patra D, Skiniotis G, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae, PS. Conformationally preorganized diastereomeric norbornane-based maltosides (NBMs) for membrane protein study: Implications of detergent kink for micellar properties. J. Am. Chem. Soc. (2017) 139: 3072-81

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22 Ehsan M*, Du Y* (* co-first author), Scull NJ, Tikhonova E, Tarrasch J, Mortensen JS, Loland CJ, Skiniotis G, Guan L, Byrne B, Kobilka BK, Chae PS. Highly Branched Penta-Saccharide-Bearing Amphiphiles for Membrane Protein Studies. J. Am. Chem. Soc. (2016) 138: 3789-96

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21 Sadaf A*, Du Y* (* co-first author), Hariharan P, Mortensen JS, Perez IM, Seven AB, Santillan C, Skiniotis G, Loland CJ, Kobilka BK, Guan L, Byrne B, Chae PS. Dendronic trimaltoside amphiphiles (DTMs) for membrane protein structure study. Chemical Science, accepted

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20 Duc NM*, Du Y* (* co-first author), Thorsen TS, Lee SY, Zhang C, Kato H, Kobilka BK, Chung KY. Effective Application of Bicelles for Conformational Analysis of G Protein-Coupled Receptors by Hydrogen/Deuterium Exchange Mass Spectrometry. J. Am. Soc. Mass. Spectrom. (2015) 26: 808-817

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19 Ehsan M, Ghani L, Du Y, Mortensen JS, Ribeiro O, Hu H, Skiniotis G, Loland CJ, Kobilka BK, Byrne B, Chae PS. New penta-saccharide-bearing tripod amphiphiles for membrane protein structure studies. Analyst, 2017. doi: 10.1039/c7an01168g

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18 Hussain H, Du Y, Tikhonova E, Mortensen JS, Ribeiro O, Santillan C, Das M, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Resorcinarene-based facial glycosides: implication of detergent flexibility on membrane protein stability. Chemistry (2017) doi: 10.1002/chem.201605016

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17 Hussain H, Mortensen JS, Du Y, Santillan C, Ribeiro O, Go J, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Tandem malonate-based glucosides (TMGs) for membrane protein structural study. Scientific Reports (2017) doi: 10.1039/c6cc06147h

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16 Woldring DR, Holec PV, Stern LA, Du Y, Hackel, BJ. A gradient of sitewise diversity promotes evolutionary fitness for binder discovery in a three-helix bundle protein scaffold. Biochemistry (2017) 56: 1656-1671

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15 Das M, Du Y, Mortensen JS, Ribeiro O, Loland CJ, Kobilka BK, Byrne B, Chae PS. Butane-1,2,3,4-tetraol-based Amphiphilic Stereoisomers for Membrane Protein Study: Importance of Chirality in the Hydrophobic Region. Chemical Science (2017) 8: 1169-1177

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14 Cho KH, Scull NJ, Du Y, Hariharan P, Mortensen JS, Loland CJ, Guan L, Kobilka BK, Byrne B, Chae PS. Mesitylene-cored glucoside amphiphiles (MGAs) for membrane protein study: importance of alkyl chain density in detergent efficacy. Chemistry (2016) 10.1002/chem.201603338

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13 Bae HE, Mortensen JS, Ribeiro O, Du Y, Ehsan M, Kobilka BK, Loland CJ, Byrne B, Chae PS. Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilization. Chemical Communications (2016) 52: 12104-12107

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12 Cho KH, Hariharan P, Mortensen JS, Du Y, Nielsen AK, Byrne B, Kobilka BK, Loland CJ, Guan L, Chae PS. Isomeric detergent comparison for membrane proteins stability: importance of inter alkyl chain distance and alkyl chain length. ChemBioChem (2016) 17:2334-2339

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11 Carr R 3rd, Schilling J, Song J, Carter RL, Du Y, Yoo SM, Cheung JY, Tilley DG, Benovic JL. β-arrestin-biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction. Proc. Natl. Acad. Sci. (2016) 113: 4107-16

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10 DeVree B, Mahoney J, Velez-Ruiz G, Rasmussen SGF, Kuszak A, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt R, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. Allosteric coupling from G protein to the agonist binding pocket in GPCRs. Nature (2016) 535 (7610):182-6

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9 Tian X, Irannejad R, Bowman SL, Du Y, Puthenveedu MA, Zastrow M, and Benovic JL. The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor. J. Biol. Chem. (2016) 291: 14510-25

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8 Hussain H, Du Y, Scull NJ, Mortensen JS, Tarrasch J, Loland CJ, Bernadette Byrne B, Kobilka BK, and Chae PS. Accessible mannitol-based amphiphiles (MNAs) for membrane protein solubilisation and stabilization. Chemistry (2016) 22: 7068-73

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7 Cho KH, Du Y, Scull NJ, Hariharan P, Gotfryd K, Loland CJ, Guan L, Byrne B, Kobilka BK, Chae PS. Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation. Chemistry (2015) 21: 10008-13

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6 Carr R 3rd, Du Y, Quoyer J, Panettieri RA Jr, Janz JM, Bouvier M, Kobilka BK, Benovic JL. Development and characterization of pepducins as Gs-biased allosteric agonists. J. Biol. Chem. (2014) 289: 35668-84.

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5 Du Y, Cheng W, Li WF. Expression profiling reveals an unexpected growth-stimulating effect of surplus iron on the yeast Saccharomyces cerevisiae. Mol. and Cells. (2012) 34: 127-132.

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4 Du Y* (* co-first author), Shi WW*, He YX, Yang YH, Zhou CZ, Chen Y. Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC. Biochemical J. (2011) 436: 283-289.

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3 Du Y* (* co-first author), He YX*, Zhang ZY, Yang YH, Shi WW, Frolet C, Di Guilmi AM, Vernet T, Zhou CZ, and Chen Y. Crystal structure of the mucin-binding protein of Spr1345 from Streptococcus pneumoniae. J. of Struct. Biol. 2011, 174: 252-257.

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2 Du Y, He YX, Gaowa S, Zhang X, Chen Y, Zhang SC, Zhou CZ. Crystal structures of the apo and GDP-bound forms of a cupin-like protein BbDUF985 from Branchiostoma belcheri tsingtauense. Proteins 2010, 78(12): 2714-9.

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1 He YX, Gui L, Liu YZ, Du Y, Zhou Y, Li P, Zhou CZ. Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly. Proteins 2009, 76(1): 249-54.